vitamin b12 injection given im or sq How to Give Injections at Home to Yourself · PA Relief Is intramuscular (IM) administration of

Keep moving

Spooner LM, Olin JL

Scale Weight: While less informative than body composition, weekly weigh-ins (same day/time, fasted) establish trends

A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss

completed efficacy trials are not yet established

Study 2: Selective Small-Molecule Inhibitors (including 5-Amino-1MQ) A selective, membrane-permeable NNMT inhibitor series decreased intracellular 1-MNA, increased NAD and SAM, suppressed adipocyte lipogenesis, and reversed high-fat-diet obesity in mice