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MG was found to cause mitochondrial injury by disturbance of MMP and suppression of oxidative phosphorylation (OXPHOS) at the respiratory chain complexes contributing to a reduction of ATP production and a raise of ROS levels in mitochondrial matrix (Shangari and O'Brien, 2004

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For hypothyroid patients, this means potentially even larger levothyroxine dose adjustments would be needed

Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the study of Liver Diseases-U.S

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