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Traumatic neural injury mechanisms include notable down-stream consequences on excitotoxic injury, cerebral vascular flow, diffusion along axonal pathways, and activation of microglia

In cultured hippocampal neurons, Dihexa treatment for 5 days induced a near 3-fold increase in the number of actin-enriched spines by 41 spines/50m for Dihexa vs

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After this, samples were reduced with 10 mM dithiothreitol and alkylated with 55 mM iodoacetamide