Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II
Janciauskiene S, Welte T
20 Its target, thyroid hormone receptor beta, is predominantly expressed in the liver: apparently, even people with normal thyroid hormone levels systemically can have intrahepatic hypothyroidism, leading to hepatic steatosis and inflammation, which this drug can counteract
The results demonstrated clear superiority over placebo across all measured endpoints
Peptides as a category hold great potential for our health, as proven by all of the research on GLP-1s
However, additional trials are needed to increase the strength and granularity of the evidence in terms of, for example, safety considerations as well as benefits in people with comorbidities such as diabetes and obesity, and across HF phenotypes