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Sakakeeny et al., Plasma Pyridoxal-5-Phosphate Is Inversely Associated with Systemic Markers of Inflammation in a Population of U.S

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Conventional drugs like metformin primarily exert their effects by improving IR, and studies have shown that they can modulate the gut microbiota, albeit with no significant impact on the levels of gut microbial metabolites (108)

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Sleep quality also improved among people living with chronic pain