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Combined kinetic studies and computational analysis on kojic acid analogs as tyrosinase inhibitors

S-Adenosyl methionine (SAM-e) is a naturally occurring compound in the body

In the colon, unabsorbed monosaccharides, polysaccharides, and nondigestible carbohydrates (fiber, resistant starch) are metabolized by bacterial fermentation into shortchain fatty acids [268, 272] that bind free fatty acid receptors 2 and 3, resulting in GLP1 secretion

Alzheimers Dement (2015) 11(6):60821.e7

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[49] demonstrated that an overexpression of RACK1 enhanced the activity of IGF-1R kinase, whereas, the IGF-1R-induced activation of PI3K/AKT signaling was inhibited in mouse fibroblasts and MCF-7 cells