A Nature Scientific Reports 2016 study showed GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 M over 72 hours and did NOT induce inflammatory biomarkers (IL-1, IL-8, HSPA1A, FOSL1) unlike other copper compounds, concluding GHK-Cu has a low potential of inducing skin irritation
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That sounds like science fiction, but researchers at the University of Wisconsin-Madison have taken an intriguing step in that direction
However, adverse effects included fatigue, insomnia, and small increases in fasting glucose and insulin resistance
Research suggests that GHK-Cu may influence genes involved in regeneration, antioxidant defense, and inflammation control