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Tirzepatide and semaglutide belong to a class of drugs called GLP-1 agonists, which help regulate blood sugar and appetite

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doi: 10.1124/dmd.116.070615 17 GaoX.RandellE.ZhouH.SunG

In the context of glutathione deficiency or impaired GST activity, this conjugation pathway is compromised, leading to the intracellular accumulation of reactive species and an increased risk of macromolecular damage and cellular dysfunction