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A Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al.) enrolled 338 adults with obesity and reported mean body weight reductions of up to approximately 24% over 48 weeks at the highest dose studied (12 mg weekly)

Concurrent medications and medical conditions: Patients taking GLP-1 medications often have multiple comorbidities and take other medications that may affect respiratory function

A new Biological Psychiatry review sharpens the case that GLP-1 drugs may affect addiction through brain reward circuits, not simply by reducing appetite

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In contrast, isoprenaline elevated force of contraction in left atrial preparations after rolipram from WT mice (Fig

Losing weight takes pressure off your heart and joints, decreasing your risk of chronic diseases