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Conditions such as Crohn's disease, pernicious anemia, or a history of gastric surgery may increase the risk of B12 deficiency

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Ferraris A, Torres B, Knafelz D, Barabino A, Lionetti P, de Angelis GL, Iacono G, Papadatou B, DAmato G, Di Ciommo V, Dallapiccola B, Castro M

EBioMedicine 33 , 196210 (2018)

None of the mechanisms summarized here have been independently verified in adequately powered human clinical trials of IGF-1 LR3 specifically

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However, after comparing baseline to post-intervention symptom prevalence, significant reductions in total and moderate GI symptom presence were found in IF2-P ( p 1,000 in 80% of samples)