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High glucose exposure impairs L-cell differentiation in intestinal organoids: molecular mechanisms and clinical implications

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Burgess S, Davey Smith G, Davies NM, et al

If people have hyperglycemia (high blood glucose), high blood pressure, or high cholesterol for a long period of time, this can lead to blood vessel damage and poor circulation (blood flow). In the case of people who bruise due to injection of medications or through glucose monitoring (with fingersticks or CGM), it is important to use new needles and lancets each time and rotate injection and testing sites, says Dr

MounjaroTM (tirzepatide) injection, for subcutaneous use: US prescribing information (2022)