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In colorectal cancer patients treated with the FOLFOX regimen (fluorouracil, calcium folinate combined with oxaliplatin), platinum residues remain detectable in dermal collagen fibers up to 60 months post-withdrawal, mediating persistent, distally distributed neuropathy via damaging cutaneous sensory nerve fibers (Cao et al

STEP Trials : These trials focused on the weight management aspect of GLP-1 therapy

doi: 10.1016/j.neuron.2014.07.027 [DOI] [PubMed] [Google Scholar] 18

The Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study found that youth (aged 10 to 17 years) with T2DM experienced a 20% to 35% annual decline in -cell function, which is significantly higher than the ~7% decline seen in older individuals [43-45]

L-Carnitine: L-Carnitine is an amino acid derivative essential for fat metabolism and energy production

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