Journal of applied physiology , 110 3, 774-80
In this process, ferroptosis plays several critical roles (Miao et al., 2022)
10.1104/pp.106.085506 17 ChewO.WhelanJ.MillarA
This work is published in Nature Chemistry in the paper, Photoacoustic imaging of elevated glutathione in models of lung cancer for companion diagnostic applications. Glutathione is abundant in most cells
Several dietary and genetic factors, including folate, vitamin B 6 , and vitamin B 12 deficiency, and known genetic variants of the MTHFR and CBS genes, influence the efficiency of H 2 S production, and could be important contributors to hypertension in these individuals, which may also explain individual responsiveness to garlic supplementation seen in clinical trials
Antioxidant Defense and Redox Balance Glutathione serves as the bodys primary intracellular antioxidant by neutralizing reactive oxygen species (ROS) and other free radicals generated during normal cellular metabolism