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Sagging and laxity result when the rate of fat loss exceeds the rate of skin retraction, especially when weight loss is rapid, collagen quality is reduced, or the patient already has early laxity

The Wingless/Int-1 (Wnt)/-catenin pathway is also activated by GLP-1RAs, enhancing osteogenic differentiation and inhibiting adipogenesis

Malignant transformation of residual endometriosis in women on unopposed oestrogen hormone replacement therapy