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The suppression of IEG induction, specifically in the dentate gyrus, was associated with significant changes to behavioral immobility responses 24 h later, suggesting that SAMe may enhance behavioral responses after stress by suppressing the induction of IEG

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Lachowiez C, DiNardo CD, Takahashi K, Loghavi S, L-C X, Kadia TM, Daver N, Adeoti M, Short NJ, Sasaki K, Wang SA, Borthakur G, Issa GC, Maiti A, Alvarado Y, Pemmaraju N, Montalban-Bravo G, Masarova L, Yilmaz M, Jain N, Andreeff M , Garcia-Manero G, Kornblau SM, Ravandi F, Jabbour EJ, Konopleva M, MD, and Kantarjian H

Davies, L

Glutathione can also be taken as a dietary supplement