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HbA1c improvements are typically assessed at 3 months after starting treatment and following each dose escalation

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5-Amino-1-methylquinolinium iodide is the lead first-in-class small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme overexpressed in white adipose tissue of obese individuals where it consumes the methyl-donor pool and depletes tissue NAD

Therefore, the authors suggested a maximum single dose and maximum total daily dose of D-allulose of 04 g/kg body weight and 09 g/kg body weight, respectively