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Therefore, SQOR is not only a key molecule for understanding the pathophysiological mechanisms of these complex diseases, but is also increasingly being recognized as a promising therapeutic target and diagnostic biomarker (Lee et al., 2024

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Curcumin suppresses NF-B, MAPK, and JAK/STAT signaling, downregulating pro-inflammatory cytokines (IL-1, IL-6, TNF-) while enhancing anti-inflammatory IL-10

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PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes

In one multicenter study, GLP-1 medicine use was associated with lower risks of major heart events, blood clots, kidney disease progression, and death compared with DPP-4 inhibitor medicines in patients with lupus and type 2 diabetes