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Methods A prospective, split-face trial was conducted on 20 patients with melasma during November 2023July 2024

It also highlighted the downregulation of DUSP4, DUSP5, and GO terms linked to MAP kinase phosphatase (MKP) activity ( Figure 5d )

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For step-by-step injection technique, see the peptide injection guide

Initially identified in rabbit brain extracts, DSIP has been observed to interact with the central nervous system, playing a role in promoting natural sleep rhythms