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More than that is concerning because of the potential for breakdown of muscle mass which can cause kidney damage

Acknowledgements We would like to thank the Kyoto Integrated Science & Technology Bio-Analysis Center for allowing us to use their LC-MS/MS (3200 QTRAP) and Editage (www.editage.jp) for English language editing

Diarrhea, constipation, and vomiting occur in varying degrees among patients

Subtle or no changes indicate the peptide may have survived exposure intact

While important to select a cancer cell-specific antigen, the prediction of total efficacy of ADCs based on the antigen expression level remains elusive (Damelin et

Oncogene 25 , 44214428 (2006)