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The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons

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CYP7A1 is the rate-limiting enzyme in converting cholesterol to bile acids, and LXRs, which function as cholesterol sensors, increase Cyp7a1 expression in response to acute cholesterol intake in mice [2,33]

A key consideration in the safety comparison is administration route