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Also called underactive thyroid or Hashimoto s thyroiditis , hypothyroidism is an endocrine disorder describing low levels of thyroxine (T4) or triiodothyronine (T3) or high levels of thyroid-stimulating hormone (TSH)

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Studies have shown that it inhibits the mRNA and protein expression of CYP1A2, CYP2D6 and CYP3A4 ( in vivo and in vitro (Yan et al., 2018)