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doi: 10.1080/19490976.2023.2293312 194 CarrollIMAndrusJMBruno-BrcenaJMKlaenhammerTRHassanHMThreadgillDS

As a triple agonist targeting GLP-1, GIP and glucagon receptors, it delivers comparable weight loss around 24% body weight reduction over 48 weeks in clinical trials while the GIP pathway actively preserves muscle

Several anticancer drugs that inhibit nucleotide metabolism induce apoptosis

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Antioxidants such as polyphenols, vitamins, alkaloids, polysaccharides, and active peptides (Figure 1) help to maintain the structure and function of neurons and prolong their healthy state ( FIGURE 1 Polyphenols Polyphenols are the most abundant antioxidant in plants and have an excellent ability to capture oxidative free radicals (Jiang et al., 2016)

In the absence of sufficient glutathione buffering, oxidative damage accumulates in pancreatic -cells, hepatocytes, adipocytes, and vascular tissues