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Graefe-Mody U, Huettner S, Sthle H, Ring A, Dugi KA
The molecule consists of a modified GLP-1 analog, containing three key amino acid substitutions: Ala8Gly, Gly22Glu, and Arg36Gly, covalently fused to the Fc (constant) region of human immunoglobulin G subclass 4 (IgG4) (Fig
Glucagon-like peptide-1 in diabetes care: can glycaemic control be achieved without nausea and vomiting
2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial
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Radioligand binding assay FlpInCHO-hGLP-1R and FlpInCHO-pGLP-1R cells were seeded at a density of 3 10 4 cells/well and INS-1(832/13) cells at 10 5 cells/well into 96-well culture plates and incubated overnight at 37 C in 5% CO 2
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