To further investigate size of nano-micelles, dynamic light scattering was utilized to characterize their mean hydrodynamic diameter (105.7 15.7 nm, as illustrated in Figure 2C), which was consistent with the above data
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The inhibition of oxidative stress, inflammation, fibrosis, and induction of natriuresis have been mainly implicated as mechanisms underlying the attenuation of DKD by GLP-1RAs ( Figure 1 )
Similarly, the exposure of human dopaminergic SH- SY5Y cells to rotenone caused the nuclear translocation of nuclear factor B (NF-B) and the activation of caspase-3, suggesting that complex I deficiency induced by rotenone can induce NF-B-mediated apoptosis (Figure 3) [68]