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Platelets are loaded with healing and repairing factors, such as PDGF, EGF, VEGF, TGF-, TF, etc., and with growth factors as well as cytokines and chemokines that mobilize bone marrow progenitor cells, which are attracted to the lesion sites and also secrete repairing factors [17,18,19]

LR3 IGF-1 is a modified analog of human IGF-1 with a 13-amino acid extension at the N-terminus and a substitution of Arg at position 3, which significantly reduces its affinity for IGF-binding proteins

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The flip side is that stacking introduces variables

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