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Notably, a three-year follow-up confirmed elevated plasma TMAO as a significant predictor of major adverse cardiovascular events (157)

Laboratory investigation typically includes comprehensive metabolic panel, magnesium level, creatine kinase (if muscle injury is suspected), and possibly vitamin D level

The corresponding author (Malay Kumar Adak) gratefully acknowledges the DST PURSE program of the University of Kalyani [Award No.: SR/PURSE Phase 2/37(G)]

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These findings are supported by previous evidence from randomized controlled trials, although results remain mixed

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