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Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration

Mounjaro was first approved by the FDA in May 2022 to treat type 2 diabetes, and Zepbound was approved by the FDA in November 2023 for long-term weight loss in adults with both obesity and either diabetes or an increased risk for a cardiovascular condition

They also work best when combined with nutritional and lifestyle changes

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The act of walking around gently after meals (if comfortable) can stimulate digestion and further prevent discomfort

The 24-hour nutrition window around injection The 12 hours before and 12 hours after your injection represent the most critical nutrition window of your week