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Some users may experience mild skin irritation or digestive discomfort, depending on individual sensitivities

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Semaglutide GLP-1 also improves glycemic control, though its effect may be slightly less pronounced

*Correspondence: Baptist Gallwitz, [email protected] This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

More serious risks include pancreatitis, gallbladder disease, acute kidney injury (particularly with dehydration), hypoglycemia (when combined with insulin or sulfonylureas), and thyroid C-cell tumors in animal studies