10.1016/j.clinbiochem.2012.09.009 42 Fernndez-de-Las-PeasC.de-la-Llave-RincnA
The accumulation of free radicals in the body overwhelms the natural antioxidant mechanisms, causing oxidative stress, which is linked to the development and progression of NCDs
Expression of the Bcl-2 protein family prevents the induction of apoptosis by a variety of oxidative stresses, including ionizing radiation, heat shock, or inhibition of GSH synthesis
Bone broth and high-quality protein sources can help
Considering the absence of a clear NLS (nuclear localization signal), this nuclear localization is more likely due to a passive diffusion through nuclear pore rather than to a specific targeting
291-301, DOI:10.1111/j.1471-4159.2010.06764.x, PMID 20438613