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In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation

also, heart beat disorders during neonatal period, hypotonia with unexplained failure to thrive, retinitis pigmentosa, or even muscle pain triggered by exercise 8

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Methods 64 , 207215 (2005)

Avoid repeated freeze-thaw cycles of reconstituted solutions, as temperature fluctuations may lead to peptide degradation and reduced biological activity

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