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According to the MHRA/EMC Summary of Product Characteristics, these include: Very common (may affect more than 1 in 10 people): Nausea Diarrhoea Common (may affect up to 1 in 10 people): Vomiting Abdominal pain Constipation Dyspepsia (indigestion) Decreased appetite These symptoms typically diminish over time as the body adjusts to the medication

The observation that the insulinotropic actions of GLP-1 are reduced in type 2 diabetes mellitus (T2DM) led to the development of incretin-based therapies GLP-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of hyperglycaemia in these patients

doi: 10.1080/15384101.2019.1638190 84 PanXGongNZhaoJYuZGuFChenJet al

Zajedno, navedeni efekti Retatrutida, delovanjem na receptore GIP, GLP-1 i GCG, ne samo da smanjuju unos kalorija, ve i podstiu mravljenje poboljanjem metabolike efikasnosti