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Notably, a clinical study demonstrated that T2DM patients receiving insulin therapy experienced significantly higher rates of pancreatitis compared to those treated with GLP-1RAs, and notably, no pancreatitis cases have been reported in clinical trials of the novel GLP-1RA Cotadutide, indicating that a comprehensive risk assessment of GLP-1RAs for pancreatic cancer remains premature pending additional data on these novel medications [8]
Diabetologia 53 (Suppl
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Currently, it is not known if increasing circulating GLP1 using oral compounds would confer the same protective effects against olanzapine-induced hyperglycemia as GLP1 receptor agonism
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