This cellular architecture enables them to respond to pathogen-associated molecular patterns through transcription and translation, thereby conferring immunocompetence
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Grossmann, M., Nakamura, Y., Grumont, R
In fact, platelet-activating factor binding to PAFr leads to the production of inositol trisphosphate (IP3) through the phosphatidylinositol cycle, which in turn binds to inositol 1,4,5-triphosphate receptor type 1 (IP3R1) to induce the release of Ca 2+ stored in the endoplasmic reticulum (Kroegel et al., 1989
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