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Structural mitochondrial abnormalities have been seen in muscle biopsies from ME/CFS patients (382), but this is not observed in other studies (383)

Prescribers must screen for contraindications including current or past seizure disorders, eating disorders (anorexia nervosa or bulimia nervosa), abrupt withdrawal from alcohol or sedatives, severe hepatic impairment, and use of other medications that lower seizure threshold

doi: 10.1111/bjd.14477

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Ghosh (2004) demonstrated that selenium significantly reduced the incidence of clinical prostate cancer