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Secondary endpoints include cardiovascular death or HF hospitalization, first and recurrent HF hospitalizations, all-cause mortality, all-cause hospitalization, a kidney composite endpoint, and major adverse cardiovascular events
Yet, without intentional policy interventions, they risk widening the gap between those who can afford them and those who cannot
The US Food and Drug Administration on Friday approved drugmaker Novo Nordisks application to add cardiovascular benefits to the medicines label, making it the first weight-loss drug to also be cleared to reduce the risk of heart attack, stroke or heart-related death in people at higher risk of these conditions
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Later developments reduced the need for washing after each coupling step 19,20,21,22 , but up to this point, washing after the deprotection step has been unavoidable
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