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Published literature going back decades doesn't show significant adverse effects at typical doses
The warning includes urging patients to contact their doctors if they experience severe or persistent gastrointestinal symptoms. Though the updated label doesnt specifically connect the warning to blockages or ileus, both conditions are associated with gastrointestinal symptoms

HYDROGENATED POLYISOBUTENE, DIISOSTEARYL MALATE, POLYISOBUTENE, TRIETHYLHEXANOIN, CERA MICROCRISTALLINA (MICROCRYSTALLINE WAX, CIRE MICROCRYSTALLINE), BIS-DIGLYCERYL POLYACYLADIPATE-2, POLYGLYCERYL-2 TRIISOSTEARATE, HYDROGENATED STYRENE/ISOPRENE COPOLYMER, SYNTHETIC WAX (CIRE SYNTHETIQUE), SILICA DIMETHYL SILYLATE, EUPHORBIA CERIFERA CERA (EUPHORBIA CERIFERA (CANDELILLA) WAX, CIRE DE CANDELILLA), BIS-BEHENYL/ISOSTEARYL/PHYTOSTERYL DIMERDILINOLEYL DIMER DILINOLEATE, PHENOXYETHANOL, PARFUM (FRAGRANCE), RUBUS IDAEUS (RASPBERRY) SEED OIL, HYDROGENATED COCONUT OIL, SQUALANE, TOCOPHERYL ACETATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, MANGIFERA INDICA (MANGO) SEED BUTTER, ASCORBYL PALMITATE, TOCOPHEROL, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE, ALUMINUM HYDROXIDE, BENZYL ALCOHOL, CI 77891 (TITANIUM DIOXIDE), CI 77491 (IRON OXIDES), CI 77492 (IRON OXIDES), CI 77499 (IRON OXIDES).

For UK patients, the most important point is that nothing has yet changed in terms of what is legally available
If you do not experience the desired results, or you have hit a weight loss plateau despite using the maximum dosage, your doctor may consider switching to another medication