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These materials are cost-effective, thermally stable, and generally regarded as safe for biomedical use

Additionally, TMAO activates NLRP3 inflammasome, resulting in the secretion of pro-inflammatory cytokines, such as IL-1, IL-6, and TNF- in human aortic endothelial cells and vascular smooth muscle cells (VSMCS) [9, 28]

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The diagnosis of CS was based on the findings in the medical record and results of physical examination, and was confirmed with magnetic resonance imaging of the brain

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