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Variants in genes like GLP1R (rs6923761), GIPR (rs1800437), and MC4R (rs17782313) may help provide context for how well you might tolerate and respond to these medications, though genetics do not predict exact medication response and should always be interpreted with a qualified provider

In the AIM-HIGH trial, in high-risk patients with cardiovascular disease, addition of prolonged-release niacin (15002000 mg/dl) to standard statin therapy did not result in additional reduction of cardiovascular events (HR = 1.02

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