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Early evidence for glutamate-mediated activity in plants came from studies on hypocotyl development under light conditions using the iGluR antagonist DNQX (6,7-dinitroquinoxaline-2,3-dione) (Lam et al
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No mechanism has been identified by which GHK-Cu would blunt metformin's glucose-lowering effect or by which metformin would impair GHK-Cu's tissue repair signaling
Importantly, the magnitude and/or absence of these effects may be dependent upon the specific GLP1 receptor agonist utilized (Beiroa et al., 2014)
