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Furthermore, sphingomyelin-derived camptothecin nanovesicles (camptothecin) can not only induce a potent granzyme-B and perforin-mediated CTLs response but also enhance the blocking effect of PD-L1/PD-1 thereby eliminating tumors (166)

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Reville PK, Nogueras-Gonzlez GM, Ravandi F, Sasaki K, Borthakur G, Garcia-Manero G, Daver N, DiNardo C, Jabbour E, Pemmaraju N, Andreeff M , Verstovsek S, Ferrajoli A, Jain N, Ohanian M, Pierce S, Estrov Z, Konopleva M, Kantarjian H, Kadia TM

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