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Yes, both GHK-Cu and AHK-Cu are legal peptides and safe to use in topical serum formulations like this one

Specifically, the Sucrosomial B12 formulation resulted in a significant increase in circulatory vitamin B12 levels from day 1 compared to baseline ( p 0.012), with levels continuing to increase until day 5 (Figure 3 boxplots, top-right)

Published Research on 5-Amino-1MQ Foundational DIO Mouse Study Neelakantan et al., Biochemical Pharmacology (2018) This paper introduced 5-Amino-1MQ as a selective and membrane-permeable small molecule inhibitor of NNMT and tested it in 3T3-L1 adipocytes and in male C57BL/6J mice maintained on a high-fat diet

However, certain groups, such as older adults and vegans, may require supplements to meet their needs

PMID: 25559140 Pawlak R