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When patients hear that TB-500 may help recovery, they should ask a more precise question: what evidence exists for this exact compound, for this exact condition, in humans, using a medically appropriate formulation and treatment plan

No head-to-head trial has compared them, so better cannot be answered directly

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The ESSENCE findings are summarized in Figure 1A

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The strengths of our study include its underlying randomized controlled design, standardized surgical techniques, and well-matched cohorts in terms of sex, age, and T2DM status