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What to Expect With Once-Weekly Tirzepatide at PlexusDx Most patients begin tirzepatide at 2.5 mg weekly and follow a four-week dose-escalation schedule: 5 mg, 7.5 mg, 10 mg, 12.5 mg, and up to 15 mg if needed and tolerated

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Mol Cell Biol (2001) 21:831828

People become worried because of early studies in animals about rodents developing thyroid C-cell tumours when high amounts of semaglutide were used on them