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Convenience: Oral wins for needle-avoidance

Tirzepatide's SURMOUNT-1 curve flattened earlier at a lower ceiling, consistent with a mechanism that primarily caps intake rather than also raising expenditure

If dietary measures are not sufficient, over-the-counter osmotic laxatives can provide relief without interfering with the peptide mechanism

Similarly, in rats injected with monoclonal antibodies (mAbs) in the hippocampus, pre-treatment with liraglutide significantly protected from the mAbs-induced damage of spatial memory and long-term potentiation (51)

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