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An elevated methylmalonic acid (MMA) level has been thought to be the most direct, metabolic indicator of B12 deficiency because B12 is the only cofactor required by the enzyme that degrades MMA

AOD-9604 Protocol Standard Dose: 250-300mcg daily Advanced Dose: Up to 500mcg daily for more aggressive goals Timing: Usually taken before bed AOD-9604 has a better safety profile for longer use

This targeted formula is perfect if you are looking for a potent dose of methyl-free B12 and folate for yourmethylation-support protocol.

It happens because the medication slows gastric emptying, which can cause feelings of queasiness or upset stomach