Xiong TT, He P, Zhou M, Zhong D, Yang T, He WH, et al
For fatigue: Ensure adequate protein intake (0.7 to 1.0 grams per pound of body weight daily)
While consistency is preferred for minimizing side effects, a 24-hour adjustment is generally considered safe within clinical guidelines
Normal cold sensitivity associated with weight loss during GLP-1 therapy typically presents as: A general feeling of being cooler than before treatment commenced Needing extra layers of clothing or preferring warmer environments Cold hands and feet, particularly in cool weather Symptoms that correlate with the amount of weight lost No other concerning features such as extreme fatigue, confusion, or changes in heart rate These sensations usually stabilise once weight loss plateaus and the body adjusts to its new composition
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Biomarkers of oxidative stress, including reduced glutathione (GSH), oxidized glutathione (GSSG) and glutathione redox/antioxidant capacity (GSH/GSSG), were measured
