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Small, microscopic bubbles are generally not harmful in subcutaneous injections, but large bubbles should be removed to ensure dosing accuracy

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By reversibly binding glucokinase (GK), GCKR modulates GKs localization and enzymatic activity, serving as both a metabolic sensor and a safeguard against excessive glucose flux (94)

The availability of a dedicated single-dose pen also offers a more convenient treatment experience, allowing patients to receive their full weekly dose in one injection