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Prescription GLP-1 receptor agonists work by directly binding to GLP-1 receptors and activating them continuously
Trends in Sport Sciences, 31(3), 139149
Biliopancreatic diversion and Roux-en-Y (gastric bypass) involves both shrinking the stomach, reducing the amount of food that can be eaten, and rerouting the GI tract to induce nutrient malabsorption
GLP-1 receptor agonists enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety through central nervous system pathways
-1 - Glucagon-like peptide-1 GLP-1 - 1923 , (Murlin ' -J Biol Chem 1923)
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