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Makvandi et al., 2021

Hemodynamic Effects: By inducing smooth muscle contraction in the vasculature, phenylephrine significantly increases peripheral resistance, which elevates both systolic and diastolic blood pressure (SBP & DBP)

Dual agonists such as tirzepatide and emerging triple agonists, including retatrutide, have shown superior weight-loss efficacy in adult populations

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KPV modulates inflammation and supports gut barrier integrity