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Remarkably, tirzepatide (15 mg per week) reduced body weight by up to 20.9% after 72 weeks [93], which was associated with reduced waist circumference and an overall improvement in individuals clinical profile

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Furthermore, exenatide has been demonstrated to inhibit the pro-inflammatory phenotypes of human PBMC-derived monocytes/macrophages through its regulatory effects on key signaling pathways, including mitogen-activated protein kinase (MAPK), NF-B and CCAAT/enhancer-binding protein beta (C/EBP) [90]

The whole arc from first consultation to a working protocol is usually two to three weeks